| 參考價 | 面議 |
測量大、小鼠尾巴部受紅外熱刺激的痛覺閾值
- 產(chǎn)品名稱：37360疼痛甩尾
- 訂貨號：tlyon000400
- 品牌名稱：意大利Ugo
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特征
優(yōu)點
儀器自動記錄實驗數(shù)據(jù)
精度高，避免人為因素引起的誤差
包含U盤和軟件
可獨立工作，也可連接電腦使用
儀器工作臺表面無突出和遮擋物件
操作方便，實驗重復性好
規(guī)格：
命令：
軟鍵和腳踏板
連接電腦：
DELTA 9-pin連接頭，USB連線
數(shù)據(jù)讀?。?/p>
液晶顯示
電源：
universal mains 85-264 VAC, 50-60Hz
打印：
微型熱敏打印機（需另外購買）
工作溫度：
15° - 30° C
開始：
紅外開關
聲級：
< 70 dB
紅外強度：
10-99級間可調(diào)
紅外光源燈泡；
Halogen "Bellaphot", Mod. 64607 OSRAM, 8V-50W
反應時間：
液晶屏顯示，分辨率為0.1s
校準：
紅外熱輻射計（需另外購買）
截止時間：
預置，15 - 60 s間
附件：
37360-325:
小鼠束縛器，25 mm I.D.
37360-330:
E-HR 002:
小鼠束縛器，30 mm I.D.
替換燈泡
37300
紅外熱輻射計
57145
微型打印機
參考文獻
方法
- F.E. D’Amour & D.L. Smith: "A Method for Determining Loss of Pain Sensation." J. Pharmacol. Exp. Therap. 72: 74-79, 1941.
涉及UB的甩尾實驗- T.O. Lilius et alia: "The Mineralocorticoid Receptor Antagonist Spironolactone Enhances Morphine Antinociception” Eur. J. of Pain online view, 2013
- J.W. Little et alia: “Spinal Mitochondrial-Derived Peroxynitrite Enhances Neuroimmune Activation During Morphine Hyperalgesia and Antinociceptive Tolerance” Pain 154 (7): 978-986, 2013
- P.J. McLaughlin et alia: “Behavioral Effects of the Novel Potent Cannabinoid CB1 Agonist AM 4054”Pharmacology Biochemistry and Behavior 109: 16-22, 2013
- T.A. Kosten et alia: “A Morphine Conjugate Vaccine Attenuates the Behavioral Effects of Morphine in Rats” Progr. in Neuro-Psychopharmacol. and Biol. Psychiatry 45: 223–229, 2013
- T.C. Chen et alia: “Spontaneous inflammatory Pain Model From a Mouse Line With N-ethyl-N-nitrosourea Mutagenesis” J. Biomed. Science 19 (55): 2–15, 2012
- J. Walsh et alia: “Disruption of Thermal Nociceptive Behaviour in Mice Mutant for the Schizophrenia-Associated Genes NRG1, COMT and DISC1” Brain Res. 1348: 114-119, 2012
- K. Guillemyn et alia: “In vivo Antinociception of Potent mu Opioid Agonist Tetrapeptide Analogues and Comparison with a Compact Opioid Agonist-neurokin 1 Receptor Antagonist Chimera” Molecular Brain5 (4): 2-11, 2012
- A.J. Morrison et alia: “Design, Synthesis, and Structure–Activity Relationships of indole-3-heterocycles as Agonists of the CB1 Receptor” Bioorganic & Medicinal Chemistry Letters 21: 506-509, 2011
- M. Spetea et alia: “In vitro and in vivo Pharmacological Profile of the 5-benzyl Analogue of 14-methoxymetopon, a Novel μ Opioid Analgesic with Reduced Propensity to Alter Motor Function” Eur. J. Pharmac. Sciences 41: 125-135, 2010
- C.A. Boehm et alia: “Midazolam Enhances the Analgesic Properties of Dexmedetomidine in the Rat”Vet. Anaesthesia and Analgesia 37 (6): 550-556, 2010
- M.A. Philips et alia: “Myg1-Deficient Mice Display Alterations in Stress-Induced Responses and Reduction of Sex-Dependent Behavioural Differences” Behav. Brain Res. 207: 182-195, 2010
- C. Dawson et alia: “ Dexmedetomidine Enhances Analgesic Action of Nitrous Oxide” Anesthesiology 100 (4): 894−904, 2004
- P. Tolu et alia: “ Effects of Long-Term Acetyl-L-carnitine Administation in Rats: I. Increased Dopamine Output in Mesocorticolimbic Areas and Protection Toward Acute Stress Exposure” Neuropsychopharmacol. 27 (3): 410-420, 2002
- R. Nadeson et alia: “ Potentiation by Ketamine of * Antinociception. I. An Experimental Study in Rats Showing that Ketamine Administered by Non-Spinal Routes Targets Spinal Cord Antinociceptive Systems” Br. J. Anaesthesia 88 (5): 685−691, 2002- L. Jasmin et alia: “ The NK1 Receptor mediates Both the Hyperalgesia and the Resistance to Morphine in Mice Lacking Noradrenaline” PNAS 99 (2): 1029−1034, 2002- G.L. Fraser et alia: “ Antihyperalgesic Effects of Opioid Agonists in a Rat Model of Chronic Inflammation” Br. J. Pharmacol. 129: 1668−1672, 2000- M. Xu et alia: “ Effects of Radolmidine, a Novel α2- Adrenergic Agonist Compared with Dexmedetomidine in Different Pain Models in the Rat” Anesthesiology 93 (2): 473−481, 2000- A. Köster et alia: “Targeted Disruption of the Orphanin Fq/Nociceptin Gene Increases Stress Susceptibility and Impairs Stress Adaptation In Mice” Neurobiology 96 (18): 10444-10449, 1999- I. Sora et alia: “Opiate Receptor Knockout Mice Define µ Receptor Roles in Endogenous Nociceptive Responses and Morphine-Induced Analgesia” Neurobiology 94: 1544-1549, 1997- C.T. Dourish et alia: "The Selective CCK-B Receptor Antagonist L-365,260 Enhances Morphine Analgesia and Prevents Morphine Tolerance in the Rat" Europ. J. Pharmacol. 176: 35-44, 1990- P.W. Nance & J. Sawinok: "Substance P-Induced Long-Term Blockade of Spinal Adrenergic Analgesia: Reversal by Morphine and Naloxone" J. Pharmacol. Exp. Therap. Vol. 240, No. 3: 972-977, 1987
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