電損毀儀于神經(jīng)化學(xué)和神經(jīng)藥理學(xué)研究。恒定的電流能夠確保測(cè)量結(jié)果有良好的重復(fù)性和由藥物對(duì)大腦皮層或大腦皮下層區(qū)域引起電休克進(jìn)行精確測(cè)定。持續(xù)的電流等級(jí)通過(guò)反饋電路形成該電路還可調(diào)節(jié)動(dòng)物間不同的阻抗。動(dòng)物阻抗能夠被預(yù)測(cè)試和顯示并且在阻抗太高而不能發(fā)出理想的電流信號(hào)時(shí)會(huì)自動(dòng)警報(bào)提示。
角膜和耳使用標(biāo)準(zhǔn)的電極也可根據(jù)實(shí)驗(yàn)人員的需要定制電極。有逆變器、雙相單元、雙極型逆變器可選。
主要技術(shù)參數(shù)
| Current Range | 10 µA to 99 mA |
| Max Electrode Resistance | 20 MO (10 µA) down to 2KO (100 mA) |
| Pulse Duration | 1-99 sec. or manually controlled |
| Compliance Volatage | 200V |
| Shipping Wt.: | 6 lbs. (2.8 kg) |
| Dimensions (cm): | 25 x 15 x 11 |
可根據(jù)需要選擇電休克儀
電休克儀
Electroconvulsive Device is designed for inducing convulsions in research animals. Consistent reproducible current levels are produced by feedback circuitry that adjust for variance in impedance of the contact from animal to animal.
主要技術(shù)參數(shù)
| Frequency | 1-299 pulses/sec. |
| Shock Duration | 0.1-9.9 sec. |
| Compliance Voltage | 2.5 kV |
| Current Range | 1-99mA |
| Output Impedance | 0 Ohm to 25 kOhm |
| Pulse Width | 0.1 - 0.9 ms. |
| Pulse Rise and Fall Time | 20 µs |
| LED Display | 0 to 199 kOhm |
相關(guān)引用文獻(xiàn)
S.M. Fortin et alia“Sampling Phasic Dopamine Signaling with Fast-Scan Cyclic Voltammetry in Awake, Behaving Rats” Current Protocols in Neuroscience, UNIT 7.25, published online 5 Jan 2015
§ V.D. Campese et alia“Lesions of lateral or central amygdala abolish aversive Pavlovian-to-instrumental transfer in rats” front Behav Neurosci. 8161, 2014
§ M.G. McCue et alia“Medial Amygdala Lesions Selectively Block Aversive Pavlovian–Instrumental Transfer in Rats” front Behav Neurosci. 8329, 2014
§ Stroobants et alia“PIncreased gait variability in mice with small cerebellar cortex lesions and normal rotarod performance” Behav. Brain Res. 24132-37, 2013
§ L.B. Cruz et alia“Effect of the bone marrow cell transplantation on elevated plus-maze performance in hippocampal-injured mice” Behav. Brain Res. available online Apr. 2013
§ M.B. Gomes et alia“Glucose levels Observed in Daily Clinical Practice induce Endothelial Dysfunction in the Rabbit Macro- and Microcirculation” Fund. & Clin. Pharmacol. 18 (3), 2004
§ C. Hamani et alia“Bilateral Anterior Thalamic Nucleus Lesions and High-frequency Stimulation Are Protective against Pilocarpine-induced Seizures and Status Epilepticus”Neurosurgery, 54 (1)191-197, 2004
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