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ORAI1抗體Anti-ORAI1 antibody
點(diǎn)擊次數(shù)：463 發(fā)布時(shí)間：2014-11-11
Anti-ORAI1抗體
From:ABCAM
Catalog Number :RS-7415R
Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ） Background: Annexin V （ANX5） is a member of a family of calcium-dependent phospholipid binding proteins.
Orai1 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins. Localizing to the plasma membrane, Orai1 plays an important role in store-operated calcium （SOC） entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response. Orai1 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1.
Anti-ORAI1抗體
Specificity : Anti-ORAI1a rabbit polyclonal antibodyspecific for ORAI1of Human,Mouse,Rat,sheep,
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– Protein G affinity chromatography purification, purity :>95%
– Isotype: IgG
– mol wt: 29kDa
Application :
– WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
– not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user..
optimal dilutions/concentrations should be determined by the end user..
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Anti-ORAI1抗體